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Laboratory tests of a novel serotonin-binding compound have revealed an unexpected disconnect between receptor activation and behavior, raising new questions about how psychedelic effects emerge in the brain. In past studies, psychedelic drugs have usually produced a predictable behavioral response in mice . Activation of the brain’s serotonin 5-HT2A receptor typically leads to rapid head-twitch movements, which researchers use as a standard indicator of hallucinogenic effects. When scientists administered a newly synthesized compound known as D5 to mice , this response did not occur. Although D5 activated the same receptor associated with classic psychedelics , it did not cause head-twitch behavior. This result was unexpected for neuroscientists who study the connection between perception and serotonin signaling. Researchers at the University of California-Davis and other collaborating institutions reported the finding in the Journal of the American Chemical Society . It raises a basic but unresolved question about how closely psychedelic effects are tied to the brain pathways believed to produce them. Psychedelic Signaling Behavior The 5-HT2A receptor is a central focus in psychedelic neuroscience. Well-known compounds like LSD and psilocybin bind to these receptors in the brain’s cortex, changing neural signaling in ways that can alter perception and shift consciousness. This

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Ayrshire Live Prestwick Councillors approved significant changes to the clubs premises license, a major part of the clubs redevelopment plans.Prestwick Golf Club has been given the green light to make significant changes to its drinks license. In its application for a variation to its premises license, the club said that it would pave the way for the final stage of a major clubhouse redevelopment. The club’s licence was originally granted in 2009 and has seen minimal changes since. Licensing Standards Officer Catrina Andrews told South Ayrshire Licensing Board that discussions had taken place over several months to ensure the updated licence would support the long-term sustainability of the historic members’ club. A full renovation of the upper floor of the clubhouse is now nearing completion. The work includes new office space alongside a modernised bar and restaurant area, accessed directly from the main street. The investment was described as important to improve both safety and the overall standard of the premises.  » Read More

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New WhatsApp beta feature lets users instantly review the audience and reshare rules of any active status By The News Digital January 16, 2026 WhatsApp adds in-status privacy check to show who can see your updates WhatsApp is reportedly testing a new feature to upgrade its status privacy. The feature spotted in the WhatsApp beta for Android version 2.26.2.9 will be located in WhatsApp status privacy, clearer and easier to use, and will allow people to check who their status update was shared with, what privacy option was used, and whether the post can be reshared. The feature makes it easier for the users who frequently adjust their WhatsApp status privacy settings before posting. Until now, WhatsApp did not offer a direct way to confirm the audience of a status after it went live. Users often had to rely on memory or delete the update if they were unsure. How does the WhatsApp status privacy check work? According to WABetaInfo, the new feature can be seen in the viewer's menu of a status that is active within the 24-hour window. When users open the menu, they may see a new section called "Audience". Tapping it opens a summary page showing the

The social media app is rolling out new 2026 features on its Edits app for creators.  Additions include the ability to: Add links to an Instagram account or reel, which when exported from Edits become a clickable overlay A weekly ideas section, which hosts ten new suggestions based on Reels previously shared 25 new video effects, including bounce, fisheye and blackout. A way to add multiple takes of audio and video clips to your storyboard, easing editing access Ideas for new Instagram Edit features Effect your audience. Experiment with the new effects to try out visuals that fit your artist or any upcoming campaigns. Leaning into early noughties nostalgia? Try the fisheye effect. Link away. Use the new links feature to easily direct fans to a collaborator’s account on a Reel, like a featured artist or hosting venue. 

Memphis man charged with rape, kidnapping used SnapChat to find 13-year-old girl's location, records show A Memphis man was charged with rape and kidnapping a 13-year-old girl the day before Christmas after he allegedly used SnapChat to track down her location, records show.